Vol. 13 No. 7-14 (2022): ANTIBIOTICS SUSCEPTIBILITY PROFILE OF E scherichia coli FROM FERMENTED MILK (N ono ) SOLD IN LAPAI, NIGER STATE, NIGERIA.

The antibiotics susceptibility profile of Escherichia coli from fermented cow milk (Nono ) was

investigated. Nono samples were collected from the Main and Badeggi markets twice a

month (four times) in April and May 2021. The pour plate technique was used to determine

the bacteria count in Nono. Identification of bacteria isolates from the sample was carried out

by subjecting the isolates to different biochemical tests. Kirby Bauer disc diffusion method

was used to determine the sensitivity of the isolates to the antibiotics (Tarivid, Reflacine,

Ciprofloxacin, Streptomycin, Augmentin, Gentamycin, Ceporex, Nalidixic acid, Septrin, and

Ampicillin) used in the study. Mean bacteria count ranged from 4.2 x 104 to 2.9 x 106cfu/ml.

From the four samplings carried out across the two (2) markets in Lapai metropolis, the

highest mean bacterial count of 2.9 x 106 cfu/ml at the dilution factor of 10-5 occurred at the

Badeggi market, while the least colony count of 4.2 x 104 cfu/ml at the dilution factor of 10-3

also occurred at Badeggi market. The incidence of bacteria isolates indicated that the highest

population was Escherichia coli 4(33%), while the least population of bacteria was observed

in Pseudomonas aeruginosa and Bacillus cereus 1(8.3%). The percentage susceptibility of

bacteria isolates to the antibiotics indicated that the most active antibiotics were Ceporax

(100%) and Streptomycin (100%), and the most resisted antibiotics was ampicillin (100%).

E. coli was the most susceptible bacteria isolate to the multiple antibiotics, while P.

aeruginosa showed resistance to most antibiotics used. The study revealed high resistance to

most antibiotics by some bacteria isolated in this study, which might be likely due to the

indiscriminate use of antibiotics to treat livestock.